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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 13.03
Human Site: S181 Identified Species: 20.48
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S181 P N S G L Y G S Y P Q G Q A P
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S181 P N S G L Y G S Y P Q G Q A P
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 A152 I S G A V A P A P P S S G L G
Dog Lupus familis XP_850963 1096 118584 S182 P N P G L Y G S Y P Q G Q A P
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 F184 D P A L Q T S F K K P G S A L
Rat Rattus norvegicus NP_001102926 1095 118506 T181 P N S G P Y S T Y P Q S Q A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 L182 P P T T L N G L G T T P P L P
Chicken Gallus gallus XP_421617 1147 124543 P238 G L P L A Q P P F S G Q P V P
Frog Xenopus laevis NP_001087832 1126 123503 S181 G F Q H S Y S S S Q G P S P I
Zebra Danio Brachydanio rerio XP_700597 1315 142554 Q181 G M Q Q M T N Q M A S M Q V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 G291 H K D M L M Q G A H G Q N L I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 A224 A G P P S S Q A P P S G F Q G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 G190 M P P S G M I G G P V S N G H
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 Q30 V A E Q Q Q S Q Q Q I D Q T A
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 V104 P A Q D A Q Q V A Y G A P T T
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 6.6 93.3 N.A. 13.3 73.3 N.A. 26.6 6.6 13.3 6.6 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 100 26.6 93.3 N.A. 20 80 N.A. 33.3 13.3 13.3 13.3 N.A. N.A. 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 7 14 7 0 14 14 7 0 7 0 34 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 7 0 0 0 0 0 0 0 7 0 0 0 % D
% Glu: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 7 0 0 0 0 0 7 7 0 0 0 7 0 0 % F
% Gly: 20 7 7 27 7 0 27 14 14 0 27 34 7 7 20 % G
% His: 7 0 0 7 0 0 0 0 0 7 0 0 0 0 7 % H
% Ile: 7 0 0 0 0 0 7 0 0 0 7 0 0 0 14 % I
% Lys: 0 7 0 0 0 0 0 0 7 7 0 0 0 0 0 % K
% Leu: 0 7 0 14 34 0 0 7 0 0 0 0 0 20 7 % L
% Met: 7 7 0 7 7 14 0 0 7 0 0 7 0 0 0 % M
% Asn: 0 27 0 0 0 7 7 0 0 0 0 0 14 0 0 % N
% Pro: 40 20 27 7 7 0 14 7 14 47 7 14 20 7 40 % P
% Gln: 0 0 20 14 14 20 20 14 7 14 27 14 40 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 20 7 14 7 27 27 7 7 20 20 14 0 0 % S
% Thr: 0 0 7 7 0 14 0 7 0 7 7 0 0 14 7 % T
% Val: 7 0 0 0 7 0 0 7 0 0 7 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 34 0 0 27 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _